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  • Myc - Wikipedia
    The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN) c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this family, due to homology with the viral gene v-myc
  • MYC: there is more to it than cancer - PMC
    MYC is a pleiotropic transcription factor involved in multiple cellular processes While its mechanism of action and targets are not completely elucidated, it has a fundamental role in cellular proliferation, differentiation, metabolism, ribogenesis, and bone and vascular development
  • MYC in cancer: from undruggable target to clinical trials
    This Review provides an overview of the various strategies to inhibit MYC, focusing on the most recently described inhibitors and those that have reached clinical trials
  • MYC: Master Regulator of Cell Death and Tumor Progression
    MYC gene has become one of the most investigated oncogenes for regulating programmed cell death and tumor growth MYC is a transcription factor that regulates the expression of numerous genes involved in critical cellular processes, such as metabolism, stress response, and proliferation
  • Disrupting MYC RNA Interactions Promotes Tumor Regression
    While MYC is commonly regarded as an oncoprotein that localizes to promoters and drives transcription of protumorigenic gene programs, emerging studies suggest that its role in cancer may extend beyond its DNA-binding capacity However, the mechanisms and consequences of DNA-independent MYC activity remain poorly understood Uhl, Aziba, Löbbert, and colleagues sought to address this by using
  • MYC Gene - GeneCards | MYC Protein | MYC Antibody
    MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene Diseases associated with MYC include Burkitt Lymphomaand High-Grade B-Cell Lymphoma Double-Hit Triple-Hit
  • MYC-Driven USP10 Stabilizes SOX4, Fuels Leukemia
    In a groundbreaking new study published in Nature Communications, researchers have unveiled a pivotal molecular mechanism underlying the proliferation of thymocytes and the onset of leukemia in mice, linking the oncogenic protein MYC with the deubiquitinase enzyme USP10 and the transcription factor SOX4 This innovative research sheds light on the intricate interplay between these key factors





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