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  • von Willebrand disease and angiodysplasia: a wider view of pathogenesis . . .
    Data from the wider field of vascular malformations may lend insight and point to novel therapeutic approaches Here we review evidence linking von Willebrand factor to angiodysplasia, the associated molecular mechanisms and the implications for therapy
  • Google Scholar
    Google Scholar provides a simple way to broadly search for scholarly literature Search across a wide variety of disciplines and sources: articles, theses, books, abstracts and court opinions
  • Vascular abnormalities in patients with von Willebrand disease: A . . .
    Third, non‐patient‐level data highlight that patients with GI angiodysplasia with VWD make up a substantial portion and that vascular abnormalities are more common in VWD patients than the general population
  • Refractory bleeding from intestinal angiodysplasias successfully . . .
    Octreotide in the treatment of gastrointestinal bleeding caused by angiodysplasia in two patients with von Willebrand's disease Bowers M, McNulty O, Mayne E Br J Haematol, (3):524-527 2000 MED: 10759709 Show 1 more reference (10 of 11)
  • Gastrointestinal bleeding, angiodysplasia, cardiovascular disease, and . . .
    Recent evidence points to isolated deficiency of the largest multimers of von Willebrand factor (VWF)—known as von Willebrand syndrome type 2A (VWS-2A)—as a risk factor for bleeding from gastrointestinal (GI) angiodysplasia This disorder is not widely recognized, perhaps because most patients do not exhibit generalized hemostatic impairment (bleeding is generally restricted to GI
  • Abnormal von Willebrand factor in bleeding angiodysplasias of the . . .
    Conclusions: This study indicates that most patients with bleeding angiodysplasia or telangiectasia have a deficiency of the largest multimers of von Willebrand factor induced by a latent acquired von Willebrand disease
  • Biology of von Willebrand disease - American Society of Hematology
    A 1973 paper by Howard et al proposed the use of ristocetin as a means of VWD diagnosis, 6 and Weiss expanded upon its use in a 1975 paper on “diagnosing the von Willebrand syndrome ” 7 This creative diagnostic tool exploited the World War II era antibiotic, which caused the side effect of thrombocytopenia due to its propensity to form VWF
  • Von Willebrand Disease-Associated Angiodysplasia: Presentation of a . . .
    2 The diagnosis and treatment of recurring gastrointestinal (GI) bleeding in Von Willebrand disease is challenging, and associated with significant morbidity, as demonstrated in this case of a 14-year-old with Type 3 VWD, who presented with recurrent bleeding secondary to duodenal angiodyplasia 3
  • Small Bowel Angiodysplasia Associated with von Willebrands Disease . . .
    The association between angiodysplasia (AD) and von Willebrand's disease (vWD) was first described by Quick in 1967 The clinical course of patients with vWD and AD is characterized by multiple admissions to hospital for gastrointestinal bleeding, necessitating transfusions of packed red cells, factor VIII, and von Willebrand factor concentrates The therapeutic management of these patients is





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